The San Francisco 49ers certainly have had some bad luck so far this season and are dealing with some high-profile injuries.

San Francisco 49ers star tight end George Kittle missed his second straight practice on Friday as ESPN insider Adam Schefter ...

Brown and Odum allowed Justin Jefferson to get behind them for a 97-yard touchdown pass from Sam Darnold. Both are considered ...

The Niners will perhaps be without arguably their three most important offensive weapons, sidelined stars Christian McCaffrey ...

Justin Herbert's status for the Chargers' Week 3 game is up in the air. The QB received a questionable designation on Friday's injury report due to a high ankle sprain suffered during Los Angeles' ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

An oblique injury has kept Seattle Seahawks running back Kenneth Walker III out of the lineup. He missed their Week 2 win ...

Many top tight ends are off to a slow start, but George Kittle is one who isn't. He's the No. 1 option at the position this ...

Packers QB Jordan Love (knee) is questionable to play Sunday for the Green Bay Packers against the host Tennessee Titans.

Jordan Mason hasn’t missed yet and the good times should continue in Week 3 against the Rams, a dreadful defense with an ...

Two NFC West teams renew their rivalry as we continue our NFL odds series with a 49ers-Rams prediction and pick.