Lizzo shut down rumors her dramatic body transformation was due to Ozempic. The singer said her weight loss was the result of "five months of weight training and calorie deficit."

Long-term weight loss for patients with obesity proved mostly successful after taking prescription-only injectable semaglutide, the Cleveland Clinic found. Researchers at the nonprofit academic and research medical center identified key factors that impact the effectiveness of the widely popular medication.

Research has shown there are plenty of perks of using a medication like Ozempic for weight loss. But, given that this is a drug, there are some potential downsides to consider, too. New research published in JAMA Network Open links GLP-1 receptor agonists—a class of medications that includes semaglutide medications like Ozempic and Wegovy—to a loss of bone density.